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MODEL Listed

prot t5 xl uniref50

ProtT5-XL-UniRef50 is a specialized encoder-decoder transformer trained on the UniRef50 protein database, designed specifically for protein sequence representation. Unlike general-purpose LLMs, this model treats amino acid sequences as a language, allowing developers to leverage its pre-trained weights for downstream biological tasks such as secondary structure prediction, protein-protein interaction analysis, and mutation effect estimation. It integrates easily into PyTorch or Hugging Face pipelines as a text2text-generation model, providing a robust foundation for those building bioinformatics tools who need a model that understands the evolutionary and structural context of proteins without training from scratch.

Rostlabtext2text-generation
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01 / MODEL CARD

Model card

ProtT5-XL-UniRef50 is a specialized encoder-decoder transformer trained on the UniRef50 protein database, designed specifically for protein sequence representation. Unlike general-purpose LLMs, this model treats amino acid sequences as a language, allowing developers to leverage its pre-trained weights for downstream biological tasks such as secondary structure prediction, protein-protein interaction analysis, and mutation effect estimation. It integrates easily into PyTorch or Hugging Face pipelines as a text2text-generation model, providing a robust foundation for those building bioinformatics tools who need a model that understands the evolutionary and structural context of proteins without training from scratch.

Model typetext2text-generation
ProviderRostlab
LicenseApache-2.0
02 / FILES & VERSIONS

Model files and versions

Model cardModel description and metadata available in this entry
Listed
Source repositoryhttps://huggingface.co/Rostlab/prot_t5_xl_uniref50
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Version informationUse the source repository for the latest version
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03 / DOWNLOAD

Download this model

We recommend using the ModelScope CLI or SDK. Install ModelScope first, then choose a full snapshot, single file, SDK or Git LFS workflow.

This entry points to Hugging Face. The commands use the matching ModelScope repository format; confirm that the repository exists on ModelScope before running them. Model repository: Rostlab/prot_t5_xl_uniref50
Install ModelScope

Install the CLI and SDK dependency before downloading.

pip install modelscope
Download the full model repository

Download the complete weights, configuration and model card.

modelscope download --model Rostlab/prot_t5_xl_uniref50
Download one file to a local directory

README.md is used as an example; replace it with another repository file when needed.

modelscope download --model Rostlab/prot_t5_xl_uniref50 README.md --local_dir ./dir
Download with the SDK

Useful in Python projects and automation scripts.

from modelscope import snapshot_download
model_dir = snapshot_download('Rostlab/prot_t5_xl_uniref50')
Clone with Git

Make sure Git LFS is installed correctly.

git lfs install
git clone https://www.modelscope.cn/Rostlab/prot_t5_xl_uniref50.git
Clone without downloading LFS blobs

Fetch the repository structure first, then pull large files when needed.

GIT_LFS_SKIP_SMUDGE=1 git clone https://www.modelscope.cn/Rostlab/prot_t5_xl_uniref50.git
04 / WORKFLOW

How to use

  1. 01
    Step 1

    Read the model card and source information.

  2. 02
    Step 2

    Start with a small, non-sensitive evaluation.

  3. 03
    Step 3

    Review quality, licensing and usage limits.

  4. 04
    Step 4

    Adopt it only after validation.

05 / DISCUSSIONS

Discussions

Use this space to keep checking source information, usage experience and maintenance status.

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